What's New?

No coincidence between getting a HPV vaccination and the risk of developing Multiple Sclerosis (Paul-Ehrlich Institute 2016)

Reduction of  cardiovascular risk factors does unfortunately not lead to any protection to prevent dementia (Moll van Charante et al., Lancet 2016;388;797-805)


Evidence based treatment for Carpal tunnel syndrome: conservative treatment with splinting, steroid injections works, but operative treatment is treatment of choice. - (American Academy of Orthopedic Surgery 2016) 

Carotid endarterectomy superior and causes less complications in comparison to carotid stenting in cases of significant carotid artery stenosis . 

(Howard et al.; Lancet 2016;387:1305-11)


Multiple antiepileptic drugs during pregnancy increase the risk of foetal malformations. 

Meador KJ, Pennell PB, May RC, et al. Fetal loss and malformations in the MONEAD study of pregnant women with epilepsy. Neurology 2019; Epub 2019 Dec 5.

 

 

Some hope for Parkinsoni's patients in future: Neurology Today:

On the Hunt for a New Parkinson's Disease Therapy, Two Different Study Teams Find the Same Target for Toxic Alpha-Synuclein

 

 

Ocrelizumab first licenced drug for secondary progressive MS.

Constipation, reduced ability to smell, REM-sleep-behavioural disorders can be first signs of Parkinson's disease.

Chronic Intake of Proton-Pump-Inhibitors are a risk factor for developing dementia: Gomm et al.;2016;JAMA Neurology;73:410-416

In order to preserve hearing in severe therapy-resistant vertigo due to Meniere's disease intratympanic Methylprednisolone should be tried first before Gentamicin

Pregabalin not working for chronic back pain - Mathieson et al.; 2017;Trial of Pregabalin in acute and chronic sciatica;N Engl J Med;376:1111-20.

Risk factors for unexplained death of Epilepsy - SUDEP: regular Grand-mal-seizures; respiratory problems after seizures;prone position during sleep;non-compliance with therapy.